OraVerse (Phentolamine Mesylate Injection) - updated on RxList

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OraVerse
(phentolamine mesylate) Injection

DRUG DESCRIPTION

Phentolamine mesylate is phenol,3-[[(4,5-dihydro-1H-imidazol-2-yl)methyl](4-methyl-phenyl)amino]-,methanesulfonate(salt), a non-specific alpha adrenergic blocker.

Phentolamine mesylate USP is a white to off-white,odorless crystalline powder with a molecular weight of 377.46. It is sparinglysoluble in water, soluble in alcohol, and slightly soluble in chloroform. The empiricalformulation is C17H19N3O•CH4O3S,and the chemical structure is:

OraVerse (phentolamine mesylate) Structural Formula Illustration

OraVerse (phentolamine mesylate) Injection is a clear,colorless, sterile, non pyrogenic, isotonic, preservative free solution. Each1.7 mL cartridge contains 0.4 mg phentolamine mesylate, D-mannitol, edetatedisodium, and sodium acetate. Either acetic acid or sodium hydroxide is used asnecessary to adjust the pH.

Last reviewed on RxList: 9/20/2013
This monograph has been modified to include the generic and brand name in many instances.

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